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Join India's Largest Placement Conclave!

📅 Dates: 5th to 7th July 2024 📍 Location: Hitex Exhibition Center, Hyderabad ✨ Calling all graduates from Pharmaceutical Sciences! ✨ Register now for the Placement Conclave and seize the opportunity to learn, explore, and jumpstart your career! 🚀 Why Attend? ✅ Engage with industry leaders ✅ Explore career opportunities ✅ Network with peers and professionals ✅ Gain insights into the latest trends in pharmaceutical sciences 📲 To register, scan the QR code or click on the link below. 🔗Registration Link: https://forms.gle/z3tZdvskJvK47RL66  (copy the link and paste it on Google Chrome) 🌐 From Clinilaunch Research Institute:- Shweta, Hrishikesh, Vamshi Krishna will be there for you to help. #IndianPharmaceuticalCongress #PharmaCareers #PlacementConclave #PharmaceuticalSciences #CareerOpportunities #PharmaStudents #Networking #IndustryTrends Regards, Placement Department.

We Can Make Your Future Better.

About The Company: Lupin Digital Health Lupin Digital Health was established with a singular focus on resetting healthcare benchmarks through Digital Therapeutics (DTx). It is a fully owned subsidiary of Lupin. We are committed to improving patients' health outcomes by using technology to provide care at all times. Through scientific evidence and Machine Learning, we are developing an ecosystem that improves the health and happiness of users with chronic conditions. Our holistic care program brings together connected devices, user-friendly apps, and dedicated experts. Through these interventions, we lower the risks of subsequent issues and avoid re-hospitalization. Website: https://lupindigitalhealth.com/  Job Type: Private Hiring For: Lupin Digital Health Job Role: Clinical Research Coordinator Industry: Hospitals and Health Care Job Priority: Normal Job Nature: Office Job Position: Full time Job Location:  Kalina, Mumbai  Work Mode: Work from office Salary Range:  20,000/- + 6,000/- Expenses = Total 26,000/- Per month Experience Range: Freshers  Date Published: 28-06-2024 Valid Through: 29-06-2024 ( 11:00 AM ) Responsibilities:  1. Coordinating clinical studies 2. Patient Callings regarding program feedback 3. COE for all marketing related materials   Qualification: MBBS, BHMS, BAMS, BDS Application Link:  https://forms.gle/WrCvT63kERBKfHLq7  (Copy the link ad paste it on google chrome and fill the application) Placement Undertaking form - Placement Undertaking Form - Lupin Digital Health.docx  (kindly download the form and upload) All interested students are required to upload their resume in PDF format and rename it as "Company Name Full Name” Eg. ( Lupin Digital Health ) In case of any relevant queries, feel free to contact Shweta ( 9958282532 ) Vamshi Krishna  ( 9391161720 ) for queries. The deadline to fill out the Google Form and upload the resume before 29-06-2024  at 11:00 AM. Kindly take note of the deadline as no applications will be accepted after it. Regards, Placement Department

Hypertension

Risk factors Modifiable risk factors include unhealthy diets (excessive salt consumption, a diet high in saturated fat and trans fats, low intake of fruits and vegetables), physical inactivity, consumption of tobacco and alcohol, and being overweight or obese. In addition, there are environmental risk factors for hypertension and associated diseases, where air pollution is the most significant.  Non-modifiable risk factors include a family history of hypertension, age over 65 years and co-existing diseases such as diabetes or kidney disease. Symptoms Most people with hypertension don’t feel any symptoms. Very high blood pressures can cause headaches, blurred vision, chest pain and other symptoms.  Checking your blood pressure is the best way to know if you have high blood pressure. If hypertension isn’t treated, it can cause other health conditions like kidney disease, heart disease and stroke. People with very high blood pressure (usually 180/120 or higher) can experience symptoms including: severe headaches chest pain dizziness difficulty breathing nausea vomiting blurred vision or other vision changes anxiety confusion buzzing in the ears nosebleeds abnormal heart rhythm If you are experiencing any of these symptoms and a high blood pressure, seek care immediately. The only way to detect hypertension is to have a health professional measure blood pressure. Having blood pressure measured is quick and painless. Although individuals can measure their own blood pressure using automated devices, an evaluation by a health professional is important for assessment of risk and associated conditions. Treatment Lifestyle changes can help lower high blood pressure. These include: eating a healthy, low-salt diet losing weight being physically active quitting tobacco. If you have high blood pressure, your doctor may recommend one or more medicines. Your recommended blood pressure goal may depend on what other health conditions you have.  Blood pressure goal is less than 130/80 if you have: cardiovascular disease (heart disease or stroke) diabetes (high blood sugar) chronic kidney disease high risk for cardiovascular disease. For most people, the goal is to have a blood pressure less than 140/90.  There are several common blood pressure medicines:  ACE inhibitors including enalapril and lisinopril relax blood vessels and prevent kidney damage. Angiotensin-2 receptor blockers (ARBs) including losartan and telmisartan relax blood vessels and prevent kidney damage. Calcium channel blockers including amlodipine and felodipine relax blood vessels. Diuretics including hydrochlorothiazide and chlorthalidone eliminate extra water from the body, lowering blood pressure. Prevention Lifestyle changes can help lower high blood pressure and can help anyone with hypertension. Many who make these changes will still need to take medicine.  These lifestyle changes can help prevent and lower high blood pressure.  Do: Eat more vegetables and fruits. Sit less. Be more physically active, which can include walking, running, swimming, dancing or activities that build strength, like lifting weights. Get at least 150 minutes per week of moderate-intensity aerobic activity or 75 minutes per week of vigorous aerobic activity. Do strength building exercises 2 or more days each week. Lose weight if you’re overweight or obese. Take medicines as prescribed by your health care professional. Keep appointments with your health care professional. Don’t: eat too much salty food (try to stay under 2 grams per day) eat foods high in saturated or trans fats smoke or use tobacco drink too much alcohol (1 drink daily max for women, 2 for men) miss or share medication. Reducing hypertension prevents heart attack, stroke and kidney damage, as well as other health problems. Reduce the risks of hypertension by: reducing and managing stress regularly checking blood pressure treating high blood pressure managing other medical conditions reducing exposure to polluted air. Complications of uncontrolled hypertension Among other complications, hypertension can cause serious damage to the heart. Excessive pressure can harden arteries, decreasing the flow of blood and oxygen to the heart. This elevated pressure and reduced blood flow can cause: chest pain, also called angina; heart attack, which occurs when the blood supply to the heart is blocked and heart muscle cells die from lack of oxygen. The longer the blood flow is blocked, the greater the damage to the heart; heart failure, which occurs when the heart cannot pump enough blood and oxygen to other vital body organs; and irregular heart beat which can lead to a sudden death. Hypertension can also burst or block arteries that supply blood and oxygen to the brain, causing a stroke. In addition, hypertension can cause kidney damage, leading to kidney failure. Hypertension in low- and middle-income countries The prevalence of hypertension varies across regions and country income groups. The WHO African Region has the highest prevalence of hypertension (27%) while the WHO Region of the Americas has the lowest prevalence of hypertension (18%). The number of adults with hypertension increased from 594 million in 1975 to 1.13 billion in 2015, with the increase seen largely in low- and middle-income countries. This increase is due mainly to a rise in hypertension risk factors in those populations. WHO response The World Health Organization (WHO) supports countries to reduce hypertension as a public health problem. In 2021, WHO released a new guideline for on the pharmacological treatment of hypertension in adults. The publication provides evidence-based recommendations for the initiation of treatment of hypertension, and recommended intervals for follow-up. The document also includes target blood pressure to be achieved for control, and information on who, in the health-care system, can initiate treatment. To support governments in strengthening the prevention and control of cardiovascular disease, WHO and the United States Centers for Disease Control and Prevention (U.S. CDC) launched the Global Hearts Initiative in September 2016, which includes the HEARTS technical package. The six modules of the HEARTS technical package (Healthy-lifestyle counselling, Evidence-based treatment protocols, Access to essential medicines and technology, Risk-based management, Team-based care, and Systems for monitoring) provide a strategic approach to improve cardiovascular health in countries across the world. In September 2017, WHO began a partnership with Resolve to Save Lives, an initiative of Vital Strategies, to support national governments to implement the Global Hearts Initiative. Other partners contributing to the Global Hearts Initiative are the CDC Foundation, the Global Health Advocacy Incubator, the Johns Hopkins Bloomberg School of Public Health, the Pan American Health Organization (PAHO) and the U.S. CDC. Since implementation of the programme in 2017 in  31 countries low- and middle-income countries, 7.5 million people have been put on protocol-based hypertension treatment through person-centred models of care. These programmes demonstrate the feasibility and effectiveness of standardized hypertension control programmes.

6 Important Hormones and Their Roles in Your Body

1. T3 and T4  T3 and T4 are the two main thyroid hormones. Your thyroid regulates your metabolism, which means it plays a role in digestion, hunger, and your overall energy level. Your thyroid can make too much hormone, which is called hyperthyroidism, or it can make too little, referred to as hypothyroidism. Hypothyroidism is more common.  2. Melatonin Several hormones help to control your sleep/wake cycles or your circadian rhythm. One of them is melatonin. Sunlight prevents the production of melatonin, which is secreted by your pineal gland. As it gets dark at night, your body makes more melatonin and you get sleepier.  Your computer, cell phone and TV all reduce the amount of melatonin you produce, so either use blue blocking glasses at night or don’t use these devices 1-2 hours before bedtime.  3. Progesterone and testosterone These two hormones are sometimes called “female” and “male” hormones, because progesterone is mostly produced in the ovaries and testosterone is mainly produced in the testicles. Both hormones are involved in reproduction. When women don’t have enough progesterone, they may have irregular menstrual cycles and experience headaches or sudden mood changes and more importantly loss of sleep!. Men with low levels of testosterone may have a low sex drive, lose hair, feel fatigued, and lose muscle mass, among other symptoms.  4. Cortisol Stress, both short term and long term, triggers certain processes in your endocrine system. For example, in the classic fight-or-flight response, your body makes both cortisol and adrenaline.  When you are under long-term (chronic), stress, your body continues to make cortisol and other stress-related hormones. Chronic stress has been associated with obesity, cardiovascular disease, anxiety and depression, and a host of other problems.  5. Insulin Most everyone knows that people with Type 1 and Type 2 diabetes have high blood sugar. The hormone insulin is necessary for the cells in your body to properly use the glucose in your bloodstream. With diabetes, there’s either little-to-no insulin or the body can’t use the insulin it does have properly. Usually, before a person develops Type 2 diabetes, they have prediabetes and insulin resistance, which means they have more glucose in their bloodstream than normal because their body is not as sensitive to the insulin anymore, The blood sugar is not high enough to be diagnosed with Type 2 diabetes, but the risk of developing it is much greater.  6. Estrogen As menopause approaches, women’s bodies produce less estrogen. Estrogen is critical to bone health, and having less of it is associated with osteoporosis, a condition in which your bones become porous and much more fragile.  If your body is making too much or too little of any of these six hormones, you may have vague symptoms that you can’t quite put your finger on. You may simply feel “off” and be unable to articulate exactly what is wrong. If that’s the case, you should consider booking an appointment with us at Osteopathic Center for Healing.

Flesh-Eating Bacteria Threat:-

What is STSS? STSS, or Streptococcal Toxic Shock Syndrome, is a severe illness caused by infection with group A Streptococcus (GAS) bacteria. It is characterized by the rapid onset of shock and multi-organ failure, which can be life-threatening if not promptly treated. Symptoms and Treatment Initial symptoms of STSS include fever, chills, muscle aches, and nausea. As the disease progresses, more severe symptoms such as low blood pressure, rapid heart rate, and organ failure can occur. Treatment involves high-dose intravenous antibiotics and supportive care. Preventive Measures Preventive measures include good hygiene practices, prompt treatment of streptococcal infections, and close monitoring of wounds and skin infections. Public health education on the symptoms and risks associated with group A Streptococcus infections is also crucial for early detection and treatment. Who is at Risk? "People with an open wound are at increased risk for STSS," according to the US CDC. This includes individuals who recently had surgery or a viral infection that causes open sores. However, experts don't know how the bacteria enter the body for nearly half of people who get STSS. Similar Outbreaks in Other Countries Other countries have also experienced similar outbreaks. In late 2022, at least five European nations reported an increase in invasive group A streptococcus (iGAS) disease cases to the World Health Organization (WHO). The WHO noted that the rise in cases correlated with the lifting of COVID restrictions.

Easy-to-Use CRISPR Tests Could Change How We Diagnose COVID and Other Illnesses

When COVID first hit, waiting days for laboratory results from an ultrasensitive polymerase chain reaction (PCR) test was commonplace. Faster tests usable by anyone, anywhere, later became widely available but were far less accurate. New research paves the way for a diagnostic test that’s as quick and easy as a rapid COVID test and accurate as PCR technology. Researchers had already adapted the gene-editing technology CRISPR to identify genetic material from pathogens such as the COVID-causing SARS-CoV-2 virus. But most such efforts involved boosting or “preamplifying” the amount of DNA or RNA to be measured—­a step that requires special equipment and training. A recent study in Nature Communications shows how CRISPR-based tests can detect SARS-CoV-2, as well as a dangerous bacterium and cancer mutations, at PCR-level sensitivity without requiring preamplification. CRISPR uses cutting enzymes attached to RNA molecules that match a targeted genetic sequence (in this case, one from the pathogen being tested for). The RNA “guides” the enzyme to this target and then activates the enzyme to cut the sequence. But some varieties of CRISPR enzyme don’t stop there; once activated, they go on to chop any nearby single-stranded DNA (ssDNA). Researchers can exploit this action by setting their test to trigger a flash of fluorescence when ssDNA is cut, confirming that CRISPR’s target pathogen was present. But in that setup, each target DNA or RNA molecule activates only one cutting enzyme. To boost the signal, study senior author Ewa M. Goldys, a biomedical engineer at the University of New South Wales in Sydney, and her colleagues created tiny “nanocircles” of DNA with a short, single-stranded sequence that attaches to both ends of a target sequence. When in circular form, these strands do not trigger CRISPR enzymes. But after they’re cut, they unfold into linear DNA that CRISPR detects—activating yet more enzymes in a chain reaction. “This is easy to detect even if only a few molecules of the target are present,” Goldys says. This strategy makes CRISPR-based tests a million times more sensitive. “Removing the preamplification step allows for an elegant, simple chemistry that can be more amenable to point-of-care systems,” says Massachusetts Institute of Technology biologist Jonathan Gootenberg, who co-developed an earlier CRISPR diagnostic system. The new approach could allow for cheap test-kit components, including lateral flow strips akin to those in current rapid COVID tests—each costing a few dollars to make. The scientists’ nanocircle-based tests detected genetic material from SARS-CoV-2 and the ulcer-causing bacterium Helicobacter pylori, and they were also able to find tumor DNA circulating in mouse blood and in human plasma. Such tests can work within 15 minutes, whereas PCR typically takes an hour or more. “We believe we’ve created a technology that has a realistic chance to supersede PCR,” Goldys says. The group is collaborating with commercial partners on viral diagnosis and parasite detection in water. The first product, though, is a box of general-use nanocircles that researchers can add to existing CRISPR tests to boost sensitivity. These circles come with their own guide RNA that targets the circles’ DNA once it unfolds. The biggest hurdle will be simultaneously sensing multiple targets. Medical applications often require this capability (usually to check that tests function correctly), but Gootenberg says it will be difficult to implement. The researchers are investigating: “We don’t know how we’re going to meet [this challenge],” Goldys says, “but we’ll try.”

Fast Forward Guest Series Edition #10 ( June 21st 2024) (4-5PM)

As we are proceeding forward with our new edition themed “Unlock Innovation in Healthcare: Startup Founders Series” This month we bring you leaders, experts, and visionaries to shop your future in the healthcare industry while you will start exploring the blast on the healthcare industry knowledge with experts. In fact, #CliniLaunch wants to ensure that our early healthcare professionals or students will get valuable industry insights. 🌟 *𝑬𝒗𝒆𝒏𝒕: *“𝑭𝒂𝒔𝒕 𝑭𝒐𝒓𝒘𝒂𝒓𝒅 𝑮𝒖𝒆𝒔𝒕 𝑺𝒆𝒓𝒊𝒆𝒔 𝑬𝒅𝒊𝒕𝒊𝒐𝒏 #10" 🎯Theme: Unlock Innovation in Healthcare: Startup Founders Series 🌐 𝑴𝒆𝒆𝒕 𝑶𝒖𝒓 𝑮𝒖𝒆𝒔𝒕:  Dr. Mahendra Kumar R Bhagirath, founder & CEO at Clindus Research Solutions  📌 𝑻𝒐𝒑𝒊𝒄:  Future Trends in AI/ML Applications for Clinical Research 📆 𝑫𝒂𝒕𝒆: June 21, 2024  ⏰ 𝑬𝒗𝒆𝒏𝒕 𝑻𝒊𝒎𝒆: 04:00 PM to 05:00 PM 📍 𝑳𝒐𝒄𝒂𝒕𝒊𝒐𝒏: Online  -  Zoom Meeting 🔗 𝑴𝒆𝒆𝒕𝒊𝒏𝒈 𝑳𝒊𝒏𝒌:Click here to join Meeting ID: 862 3891 9243 Passcode:  870721 𝐆𝐮𝐞𝐬𝐭 𝐏𝐫𝐨𝐟𝐢𝐥𝐞:- 𝐃𝐫. 𝐁𝐡𝐚𝐠𝐢𝐫𝐚𝐭𝐡 is a highly 𝐞𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞𝐝 𝐦𝐞𝐝𝐢𝐜𝐚𝐥 𝐩𝐫𝐨𝐟𝐞𝐬𝐬𝐢𝐨𝐧𝐚𝐥 with a passion for both 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐩𝐫𝐚𝐜𝐭𝐢𝐜𝐞 𝐚𝐧𝐝 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡. Since graduating in 2020, he has gained valuable experience as an assistant professor, a clinical research associate, and more recently, a project manager on a government healthcare project in Bangalore, Karnataka.  Note: All attendees need to be present. Make sure to join the meeting 15 minutes early. Regards, Placement Department.

Guest Session Joining Intimation

    🌟 *𝑬𝒗𝒆𝒏𝒕: *“𝑭𝒂𝒔𝒕 𝑭𝒐𝒓𝒘𝒂𝒓𝒅 𝑮𝒖𝒆𝒔𝒕 𝑺𝒆𝒓𝒊𝒆𝒔 𝑬𝒅𝒊𝒕𝒊𝒐𝒏 #10" 🎯Theme: Unlock Innovation in Healthcare: Startup Founders Series 🌐 𝑴𝒆𝒆𝒕 𝑶𝒖𝒓 𝑮𝒖𝒆𝒔𝒕:  Mr. Bharatheesh PL, 𝐂𝐨-𝐟𝐨𝐮𝐧𝐝𝐞𝐫 & 𝐂𝐄𝐎 of Mediimpact MedPass  📌 𝑻𝒐𝒑𝒊𝒄: Digital Health & AIML in Healthcare 📆 𝑫𝒂𝒕𝒆: June 19, 2024  ⏰ 𝑬𝒗𝒆𝒏𝒕 𝑻𝒊𝒎𝒆: 04:00 PM to 05:00 PM 📍 𝑳𝒐𝒄𝒂𝒕𝒊𝒐𝒏: Online - Zoom Meeting 🔗 𝑴𝒆𝒆𝒕𝒊𝒏𝒈 𝑳𝒊𝒏𝒌:   https://us06web.zoom.us/j/86282557993?pwd=31iqgFIMbMlM3GknPhx9338dpa363H.1  Meeting ID: 862 8255 7993 Passcode:  065640